DailyMed will deliver notification of updates and additions to Drug Label data at the moment shown on this site via its RSS feed. The mechanism of motion of carisoprodol in relieving discomfort associated with acute painful musculoskeletal situations has not been clearly recognized. The pharmacokinetics of carisoprodol and its metabolite meprobamate have been studied in a crossover research of 24 healthy subjects (12 male and 12 feminine) who acquired single doses of 250 mg and 350 mg SOMA (see Table 2). The exposure of carisoprodol and meprobamate was dose proportional between the 250 mg and 350 mg doses. In 2006, the FDA required labeling changes to the package deal insert to stress the chance of abuse and dependence.
Drug interactions between sure medicine may affect the way in which a selected medication works in the physique. Results from both studies confirmed that SOMA 250 mg offered important and fast reduction of again ache compared to placebo (P = zero.0001) with efficacy comparable to SOMA 350 mg. In the research, the discontinuation rate resulting from opposed occasions for SOMA 250 mg was similar to placebo and lower than that for SOMA 350 mg (2% versus 2.7% versus 5.four% respectively). So if you decide to buy carisoprodol on-line do not forget about this fact. Carisoprodol is metabolized into hydroxycarisoprodol, hydroxymeprobamate and meprobamate. Long time period studies in animals have not been performed to evaluate the carcinogenic potential of carisoprodol.